Some of the uses of mrdh™ listed in the following publications have not been approved or cleared by the Food and Drug Administration.
J CARD SURG 2009; 24:722-724 Tomas A Salerno MD et al; Control of Troublesome Bleeding During Repair of Acute Type A Dissection with Use of Modified Rapid Deployment Hemostat (MRDH)
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Journal of Trauma 2006; 61: 739-742 David R. King, MD et al, Modified Rapid Deployment Hemostat Terminates Bleeding From Hepatic Rupture in Third Trimester
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Biomaterials 2005;26: 5433-5433 Fischer TH, Thatte HS, Nichols TC, Bender-Neal DE, Bellinger DA, Vournakis JN Synergistic Platelet Integrin Signaling and Factor XII Activation in Poly-N-acetyl Glucosamine Fiber-Mediated Hemostasis
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Journal of Trauma 2004; 57:S38 –S41 Najjar SF, Healey NA, Healey CM, McGarry T, Khan B, Thatte HS, Khuri SF Evaluation of Poly-N-Acetyl Glucosamine as a Hemostatic Agent in Patients Undergoing Cardiac Catherterization: A Double-Blind, Randomized Study
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Journal of Trauma 2004; 57:S2-S6 Vournakis JN, Demcheva M, Whitson AB, Guirca R, Pariser ER Isolation, Purification, and Characterization of Poly-N-Acetyl Glucosamine Used as a Hemostatic Agent
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Journal of Trauma 2004; 57: 756-759 King DR, Cohn SM, Proctor KG, and the Miami Clinical Trials Group Modified Rapid Deployment Hemostat Bandage Terminates Bleeding in Coagulopathic Patients with Severe Visceral Injuries
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Journal of Surgical Research 2003; 113:1-5 Vournakis JN, Demcheva M, Whitson AB, Finkielsztein S, Connolly RJ The RDH Bandage: Hemostasis and Survival in a Lethal Aortotomy Hemorrhage Model.
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Journal of Surgical Research 2002; 102:215-220 Ikeda Y, Young LH, Vournakis JN, Lefer AM Vascular Effects of Poly-N-Acetylglucosamine in Isolated Rat Aortic Rings
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Surgery 1999; 126: 510-517 Cole DJ, Connolly RJ, Chan MW, Schwaitzberg SD, Byrne TK, Adams DB, Baron PL,O’Brien PH, Metcalf JS, Demcheva M, Vournakis JN A Pilot Study Evaluating the Efficacy of a Fully Acetylated Poly-N-acetyl Glucosamine Membrane Formulation as a Topical Hemostatic Agent
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